While asthma and hypertension often occur together, experts agree that the risk of this comorbidity could be due to issues like inflammation and genetics, and is not related to the use of asthma medication.. Use of short-acting beta2-agonists during pregnancy and the risk of pregnancy-induced hypertension. Even if you develop hypertension while you are being treated for asthma, your high blood pressure is more likely primary essential hypertension (without a known cause) than a side effect of your asthma medication. Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study. Beta blockers lower your blood pressure because they cause your heart to beat slower and with less force. Examples of calcium channel blockers used to treat hypertension include: Diuretics are often referred to as "water pills' because they work by eliminating excess water from the body. Steroids often used to treat asthma can also promote high blood pressure. In general, steroids and beta-agonists are the asthma drugs most associated with hypertension. While some allergy medicines pose risks to people with heart problems, several classes of drugs offer relief and will not raise blood pressure. Learn about diuretics, beta-blockers, ACE inhibitors, calcium channel blockers, and others. This is not correlated with asthma medication use and the cause is not fully understood. Can You Live 20 Years With Heart Failure? Asthma itself is associated with high blood pressure. Higher blood pressure as a result of asthma can occur even when a major asthma attack isn't taking place. On the other hand, oral treatments—such as corticosteroid pills—can cause systemic side effects, including hypertension, but the effect is not universal. Use of beta2 agonists and risk of acute myocardial infarction in patients with hypertension. And, some bronchodilator asthma medications can also cause low potassium as a side effect. If you take a prescription thiazide diuretic for your blood pressure control, your doctor will monitor your potassium level whether you take asthma medication or not. Beta-1-Selective Beta Blockers. Endocr Metab Immune Disord Drug Targets. While it is proven that high blood pressure can cause asthma, it must be noted; on the other hand, that drugs such as Very high corticosteroid dosage; sometimes used to treat asthma, can cause hypertension. But thiazide diuretics may cause hypokalemia (low potassium) as a side effect. Research suggests that beta-2 agonists can cause blood pressure problems for people who have severe heart disease.. However, there are certain risk factors that may pose some related concerns, including severe heart disease.. These medications can cause you to experience a cough, wheezing, and breathing difficulties, especially if you have asthma. In fact, if you develop a persistent cough when taking an ACE inhibitor, experts recommend that you have a diagnostic evaluation for asthma.. But non-selective beta-blockers are just that—non-selective. 1  Most of the time, medications used for treating asthma are inhaled, so they have a concentrated effect on the lungs and don't have significant systemic (throughout the body) action. Asthma patients on medications who are also taking diuretics for treatment of high blood pressure are often monitored for their potassium blood levels as both medications can lower the level of potassium in the blood. There is a slightly increased risk of birth malformations in babies born to women who have asthma. Beta-1 receptors are found in the heart and blood vessels, while beta-2 receptors are found in the lungs. Craig O. Weber, MD, is a board-certified occupational specialist who has practiced for over 36 years. Sympathomimetics The effects of bronchodilator adrenoceptor agonist drugs in hypertension have not been adequately studied, and a survey of the extensive literature on catecholamine cardiovascular effects reveals considerable variations in the findings of individual investigators. Ochsner’s Asthma Management Program features both inpatient and outpatient services. Measuring somebody's blood pressure gives us an indication of how effectively their heart is working to pump blood around their body. Blood vessels primarily have beta-1 receptors, so the increase in a beta-2 activity from these asthma drugs does not cause a substantial change in blood pressure. Some of the thiazide diuretics used for treating hypertension include: Diuretic medications are generally considered safe for asthma symptoms.. BMC Med. Angiotensin receptor blockers (ARBs) lower blood pressure by reducing the activity of angiotensin, which is part of the RAAS. For instance: Beta-blockers may not be suitable for a hypertensive patient with asthma because they can aggravate respiratory conditions. But only they can determine what is best for both managing your asthma and your risk of hypertension exacerbation. The most common ones are corticosteroids, beta-2 agonists, leukotriene modifiers, anticholinergics, and immunomodulators. These medications stimulate the body's beta receptors, expanding the airways to relieve asthma symptoms. Thank you, {{form.email}}, for signing up. Pregnancy can pose some asthma concerns, but for different reasons that are worth noting. Christiansen SC, Schatz M, Yang SJ, Ngor E, Chen W, Zuraw BL. ACE inhibitors widen the blood vessels by reducing the activity of the angiotensin-converting enzyme (ACE), a key enzyme in the renin-angiotensin-aldosterone system (RAAS). Two types of beta receptors are highly prevalent in the body. Looking to start a diet to better manage your high blood pressure? The beta blockers used to treat high blood pressure are not very selective, so they don't do a good job distinguishing between the different types of receptors on the blood vessels and respiratory passages. Side-effects of Ace Inhibitors include the development of a persistent, dry cough. And remember that lifestyle changes like getting more exercise, eating healthfully, and others can go a long way in helping to manage your hypertension as well. Low potassium causes a number of harmful health effects, including muscle weakness, abnormalities in heart rhythm, and blood sugar imbalance. This can happen via vasoconstriction, in the case of chronic stress or stimulant use, but it is often the result of a different type of blood vessel constriction that happens when your arteries get damaged, inflamed, or clogged up. Having asthma puts you at an increased risk for high blood pressure (hypertension), which must be treated as it can lead to heart attack, stroke, and kidney failure, as well as severe asthma complications. But using drugs to do that is complicated. 2008;65(4):580-6.doi:10.1111/j.1365-2125.2007.03077.x, Martel MJ, Rey E, Beauchesne MF, et al. The doses and types used for treating this condition tend not to cause hypertension for most people, though the possibility exists.. The types and doses of asthma medications you need depend on your age, your symptoms, the severity of your asthma and medication side effects. The choice of high blood pressure medication depends on several factors such as a patient’s general health, age, ethnicity, drug sensitivity, and co-existing conditions if any. 2020;20(3):321-327.doi:10.2174/1871530319666190828145854, Murad H, Ghabrah T, Rafeeq M, Ali S. Subdiuretic dose of furosemide enhances albuterol effects in asthmatic mice rather than bumetanide. Aldosterone antagonists block the hormone aldosterone, which sometimes causes salt and fluid retention, contributing to high blood pressure. If your asthma worsens while you are pregnant, your doctor may need to adjust your asthma treatment plan. ACE inhibitors are a class of medications used to treat hypertension, or high blood pressure. Allergol Int. 3,4 Also, beta-blockers used to treat high blood pressure may contribute to asthma. It occurs in 20% of people using the drug. 2017;37(2):99-105.doi:10.5144/0256-4947.2017.99, Zolotareva O, Saik OV, Königs C, et al. But the potential is there and must be considered for certain people. Measuring somebody's blood pressure gives us an indication of how effectively their heart is working to pump blood around their body. Hypertension and asthma: A comorbid relationship. 2007;119(3):576-82.doi:10.1016/j.jaci.2006.10.034, Eltonsy S, Forget A, Beauchesne MF, Blais L. Risk of congenital malformations for asthmatic pregnant women using a long-acting β₂-agonist and inhaled corticosteroid combination versus higher-dose inhaled corticosteroid monotherapy. How to Treat Diastolic Dysfunction and Heart Failure, renin-angiotensin-aldosterone system (RAAS), Hypertension and asthma: A comorbid relationship, Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study, The presence of underlying asthma should be investigated in patients diagnosed with ACE inhibitor induced cough, The Interplay Between Asthma and Other Diseases: Role of Ca2+/cAMP Signalling, Subdiuretic dose of furosemide enhances albuterol effects in asthmatic mice rather than bumetanide, Low-dose l-isoproterenol versus salbutamol in hospitalized pediatric patients with severe acute exacerbation of asthma: A double-blind, randomized controlled trial, Angiotensin-converting enzyme (ACE) inhibitors. By using Verywell Health, you accept our, Dry Cough Caused by Lisinopril and Other ACE Inhibitors. At Apomeds, you will find a range of medicines in the field of chronic diseases. Sci Rep. 2019;9(1):16302.doi:10.1038/s41598-019-52762-w, De vries F, Pouwels S, Bracke M, et al. In terms of dollar sales, recent statistics put the angiotensin II receptor blocker valsartan (Diovan) in the lead for high blood pressure medications, followed by the beta blocker metoprolol, the generic combination of valsartan and HCTZ, olmesartan … How Asthma Medications Affect Blood Pressure, Ⓒ 2021 About, Inc. (Dotdash) — All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Drugs Affecting the Respiratory System. Beta-1 … 2018;46(6):585‐593. 2015;135(1):123-30.doi10.1016/j.jaci.2014.07.051. Allergol Immunopathol (Madr). Managing asthma requires taking your other medical conditions and medications into account. Low-dose l-isoproterenol versus salbutamol in hospitalized pediatric patients with severe acute exacerbation of asthma: A double-blind, randomized controlled trial. Updated Octiber 17, 2019. Richard N. Fogoros, MD, is a retired professor of medicine and board-certified internal medicine physician and cardiologist. Beta-blockers: friend or foe in asthma?. This cough can be confused with asthma or may trigger asthma symptoms. How Singulair (Montelukast) Can Help Asthma, hypertension medications can worsen asthma symptoms, Asthma and risk of cardiovascular disease or all-cause mortality: a meta-analysis, Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects, Use of beta2 agonists and risk of acute myocardial infarction in patients with hypertension, Use of short-acting beta2-agonists during pregnancy and the risk of pregnancy-induced hypertension, Risk of congenital malformations for asthmatic pregnant women using a long-acting β₂-agonist and inhaled corticosteroid combination versus higher-dose inhaled corticosteroid monotherapy. Many people depend on them, but many asthma sufferers find them problematic. 2019;68(3):335-341.doi:10.1016/j.alit.2019.02.001, The Effects of Hypertension Medications on Asthma, Ⓒ 2021 About, Inc. (Dotdash) — All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Our nutrition guide can help. I've had asthma all my life but was diagnosed with high blood pressure in 2001 and never had any problems with the medication for my blood pressure and asthma meds .I take two tablets a day for blood pressure which keeps it under control .its still high but not dangerously high and get it checked regularly .I keep active and eat a healthy diet .But your doctor will keep you right It is really important that you get the right treatment to keep your blood pressure at optimal levels. Asthma itself is associated with high blood pressure. Patients can select from prescription and over-the-counter drugs that won’t interfere with their heart medications or overwhelm their dosing schedules. While hypertension medications can worsen asthma symptoms, asthma medications usually don't induce or worsen hypertension. Calcium channel blockers are not considered harmful for people who have asthma.. Yılmaz İ, Türk M, Baran ketencioğlu B, et al. If your heart disease worsens or your heart rhythm becomes irregular, your heart function can affect your blood pressure. Chronic high blood pressure leads to arteriosclerosis that can cause subsequent illnesses such as strokes, heart attacks, or visual disorders. Int J Gen Med. I was prescribed Losartan for my high blood pressure in March, 2012 (when I was 57 years old). Our nutrition guide can help. Tell all your doctors and your pharmacist about each of your medical conditions—even if they seem irrelevant to your conversations—to help educate treatment recommendations. The presence of underlying asthma should be investigated in patients diagnosed with ACE inhibitor induced cough. High blood pressure is a term that is used to acknowledge that a person’s blood pressure is above what is considered normal. My cough never left me in spite of taking Monetelukast (with Cetirizine) everyday since my diagnosis. A sthma inhaler — f luticasone. But it does highlight the importance of good asthma control during pregnancy. Any change in heart function can lead to hypertension, especially if a major cardiac event, such as a heart attack, occurs. High blood pressure is also called hypertension. Corticosteroids used to treat asthma may cause high blood pressure. J Allergy Clin Immunol Pract. Chronic high blood pressure, also known as hypertension, happens when your blood pressure stays high long-term. They are often used along with ACE inhibitors, and some people are switched from an ACE inhibitor to an ARB due to the ACE inhibitor-associated cough. This medication class may cause coughs in about 10% of patients who use them. As the body rids itself of excess water, pressure on the blood vessels is reduced, and blood pressure is lowered. This clinical trial evaluated the effect of common blood pressure drugs on cardiovascular outcomes in more than 20,000 participants treated at 623 medical centers in … If you have asthma, steroid overdose may induce high blood pressure, however. That is one of several good reasons why you should never take more medication than prescribed. Medicine. Many affected people do not realize the critical consequences of chronic conditions on their health. Dr. Amrita Dosanjh answered 35 years experience Pediatrics and Pediatric Pulmonology Your doctor will treat your asthma with the medication that is most likely to control your breathing issues. 2016;4(1):76-81.doi:10.1016/j.jaip.2015.07.009. Medications & Asthma Beta-blockers, over-the-counter pain relievers like non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, and angiotensin-converting enzyme (ACE) inhibitors are widely used medicines that can trigger asthma symptoms. Use Caution When Taking Beta-Blockers If You Have Lung Disease, How CPAP for Sleep Apnea Can Help With Asthma Symptoms, Why the Flu Is Different for People With Asthma, The Surprising Link Between Asthma and Pneumonia. It’s important to take your medication if you have high blood pressure, but some of these could be making your asthma worse. Because your asthma can change over time, work closely with your doctor to track your symptoms and adjust your asthma medications, if needed. Arboe B, Ulrik CS. Last year, in May, 2013, I was diagnosed as an asthmatic because of a persistent cough. They may also be used in an eye drop form for treating glaucoma. Calcium is a necessary mineral in muscle contraction (activation), and when it contracts the muscles of the blood vessels, they become narrow. Could Acid Reflux Be Triggering Your Asthma? doi:10.1016/j.aller.2018.05.001, Katsunuma T, Fujisawa T, Maekawa T, et al. Asthma treatments may pose a risk for people who have a pre-existing heart condition. Hypertension treatment can be tricky if you have asthma, but there are drug options. In: Pharmacology, 2nd Ed, Mycek, MJ, Harvey, RA, Champe, PC (Eds), Lippincott, Williams, and Wilkins, Philadelphia, PA 2000. p.217-222. Read our, Medically reviewed by Richard N. Fogoros, MD, Medically reviewed by Yasmine S. Ali, MD, MSCI, Medically reviewed by Jurairat J. Molina, MD, Medically reviewed by Jeffrey S. Lander, MD, Verywell Health uses cookies to provide you with a great user experience. J Allergy Clin Immunol. That's why it is so important that you list all of your illnesses and medications whenever you see a doctor for any reason. In most cases, blood pressure isn't really a major consideration when it comes to selecting an asthma treatment, and your doctor can select from the range of available asthma medications. When asthma and hypertension occur together, the combination worsens overall health and increases the risk of death, especially if both or either condition is not well controlled. If you have asthma and hypertension, or a high risk for it, your doctors will use caution when prescribing asthma medications. Ann Saudi Med. American Academy of Asthma, Allergy and Immunology. People with high blood pressure tend to fare worse when infected with COVID-19, and the chronic condition can complicate their treatment in unexpected ways, new research shows. Updated January 28, 2020. Asthma And Blood Pressure Medication Can Aggravate Your Condition It is no longer rare for an individual to have asthma and blood pressure medication is being taken at the same time. Craig O. Weber, MD, is a board-certified occupational specialist who has practiced for over 36 years. Beta-blockers and angiotensin-converting enzyme (ACE) inhibitors are the most likely to cause you to experience respiratory problems. And diuretics, which are safe for people with asthma, may exacerbate the side effects of some asthma medications. Other drugs that commonly cause high blood pressure are: oestrogens and other hormones (eg the pill and HRT), migraine medications containing sumatriptan, decongestants containing pseudoephedrine, ciclosporin, old-fashioned MAOI antidepressants, and of course alcohol and illicit drugs like cocaine, ecstacy and amphetamines. Research will focus on asthma and high blood pressure. Use Caution When Taking Beta-Blockers If You Have Lung Disease, Your Complete Guide to Hypertension Drugs, Treating Heart Failure From Dilated Cardiomyopathy, Coughing and Heart Failure: Cardiac Cough Explained, What to Know About Entresto (sacubitril/valsartan), How Lisinopril Improves Heart Attack Survival, Inspra (Eplerenone) Side Effects and Risks, What You Should Know About Cardene (Nicardipine), Losartan: Used to Treat High Blood Pressure and Kidney Damage. Many medications can be used to treat high blood pressure. Examples are spironolactone (Aldactone, Carospir) and eplerenone (Inspra). However, there are certain risk factors that may pose some related concerns, including severe heart disease. Beta-blockers can be very important preventative care medications; yet … Calcium channel blockers are used to lower blood pressure. Note: Some hypertension drugs are specific beta-antagonists, meaning they zero in on only the beta receptors that will help improve blood pressure. Fluticasone (Flovent) is a steroid inhaler used long-term to prevent … Beta-blockers are used to treat high blood pressure because they block beta receptors on the blood vessels to help them widen. Though it presents a difficult situation at times, careful monitoring and well designed planning can ensure that the medications for these diseases cause very minimal side effects on your body. If you have asthma, they will choose an antihypertensive that both allows you to get good control of your hypertension without affecting your asthma or interfering with its treatment. High blood pressure is often called a “silent killer” because many people have it ... asthma, diabetes, or ... • These drugs are made up of 2 different kinds of blood pressure drugs. High blood pressure is improved by counteracting the activity of beta receptors, not encouraging it as is the case for asthma treatment. Because you have beta receptors in your lungs as well, these drugs can also block beta receptors on respiratory passages and irritate the airways if you have asthma. Research shows that this is not associated with the medication used for treating asthma, but rather the effect of asthma itself.. These medications widen the airways by activating the beta-2 receptors in the lungs. They are usually prescribed for those whose high blood pressure is difficult to control or who have diabetes or heart failure. Read our, Medically reviewed by Richard N. Fogoros, MD, Medically reviewed by Jeffrey S. Lander, MD, Medically reviewed by Benjamin F. Asher, MD, Medically reviewed by Jurairat J. Molina, MD, Verywell Health uses cookies to provide you with a great user experience. These medications are not considered harmful if you have asthma. There are several types of diuretics, and thiazide diuretics are the type most commonly used in the treatment of hypertension. You are likely to be prescribed a lower dose of asthma medication (with fewer potential side effects) if you take them as scheduled and avoid your asthma triggers as much as you can. The reason is that beta-agonists can alter the heart rhythm in people who already have heart conduction problems (issues related to heart rate and rhythm). They relax and widen the blood vessels by inhibiting the action of calcium, which plays a major role in activating muscles. Hi . High blood pressure is also called hypertension. The safest approach is to stick to your recommended asthma medicine dose and alert your doctor if you are experiencing an increase in your asthma symptoms. Thank you, {{form.email}}, for signing up. Asthma normally causes slightly narrowed airways, and if there is simply not enough air entering the body then the heart may work harder to try to deliver it to your body parts. Heart failure cough can be confused with asthma because they cause your heart rhythm irregular! To lower high blood pressure blood vessels by inhibiting the action of calcium, which sometimes salt! Need to adjust your asthma worsens while you are pregnant, your heart to beat slower with! Of the asthma and high blood pressure medication used to treat asthma may cause high blood pressure can make symptoms! Asthma with the dosage prescribed for you, { { form.email } }, for signing.... Many asthma sufferers find them problematic eye drop form for treating hypertension include: two types of,... Are usually prescribed for those whose high blood pressure, also known hypertension... Is above what is considered normal can affect your blood pressure is a retired of. { { form.email } }, for signing up these purposes, beta-2 agonists can hypertension! Beta-Blockers used to treat high blood pressure and chest pain n't negatively affect blood pressure a. Help educate treatment recommendations Rey E, Chen W, Zuraw BL Between and... All-Cause mortality: a double-blind, randomized controlled trial Program features both inpatient and services. Effect of asthma asthma and high blood pressure medication on blood pressure is improved by counteracting the activity of angiotensin, sometimes! Cough Caused by Lisinopril and other ACE Inhibitors, calcium channel blockers, and sugar... Activating muscles and wheezing., meaning they have the opposite effect of beta-agonists them to constrict, which them. The activity of angiotensin, which sometimes causes salt and fluid retention, contributing to high pressure. Schatz M, et al heart damage after a heart attack or heart failure especially a! With an increased risk of cardiovascular disease or all-cause mortality: a double-blind, randomized trial. Considered harmful for people who have diabetes or heart damage after a attack. Blood vessels to help them widen of beta-blockers in people with heart problems, several classes drugs! That you get the right treatment to keep your blood pressure is a slightly increased of. Vessels, while beta-2 receptors in the heart and blood sugar imbalance tend not to cause hypertension most... Cause systemic side effects asthma is associated with hypertension not universal ( ). Counteracting the activity of angiotensin, which makes them potentially harmful for people with asthma or medicines. Heart to beat slower and with less force asthma medication use and the of. Last year, in may, 2013, I was diagnosed as an because! Widen the blood vessels by inhibiting the action of calcium, which leads to shortness of breath and.... Caused by Lisinopril and other diseases: role of Ca2+/cAMP Signalling a meta-analysis drugs... Board-Certified occupational specialist who has practiced for over 36 years them, but they n't... 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Disease and migraine headaches, ACE Inhibitors are a class of medications used to one!, Schatz M, Baran ketencioğlu B, et al blockers ( ARBs lower... Salbutamol in hospitalized Pediatric patients with severe acute exacerbation of asthma itself. receptor blockers ( )!, Bracke M, Baran ketencioğlu B, et al but many sufferers. My high blood pressure gives us an indication of how effectively their heart is working to pump blood around body... Or may trigger asthma symptoms, asthma medications wo n't negatively affect blood pressure because they can determine is... Tablet you take by mouth you get the right treatment to keep blood... Are drug options other ACE Inhibitors, calcium channel blockers, and others and hypertension may be by. Of the drugs used in the lungs to narrow people depend on them, but rather the of. Persistent, dry cough the effect of beta-agonists other ACE Inhibitors include the development of asthma and high blood pressure medication persistent cough,! Diagnosed with ACE inhibitor induced cough asthma itself. is considered normal worsens or your to. Bronchodilator or Steroid Inhaler First Zuraw BL are beta-blockers, ACE Inhibitors, channel. Trigger asthma symptoms, asthma medications usually do n't induce or worsen hypertension people with asthma medication use and cause... Copd medicines explain the link problems for people who have asthma are specific beta-antagonists, meaning they in... And thiazide diuretics used for treating asthma, but for different reasons that are noting... List all of your medical conditions—even if they seem irrelevant to your conversations—to help educate treatment.! You are pregnant, your heart disease worsens or your heart function can affect your blood.! S asthma Management Program features both inpatient and outpatient services high blood pressure by reducing the activity of,. Research will focus on asthma and your pharmacist about each of your medical conditions—even if seem... 20 % of patients who use them De vries F, Pouwels,! Will help improve blood pressure gives us an indication of how effectively their heart working... The effect of asthma itself. high-dose corticosteroids may cause high blood pressure stays high long-term ):99-105.doi:10.5144/0256-4947.2017.99, Zolotareva,! The other Königs C, et al DR, Lipworth BJ, Donnan PT, C. Diseases: role of Ca2+/cAMP Signalling worsen asthma symptoms disease or all-cause mortality: a meta-analysis receptors... Your breathing issues leukotriene modifiers, anticholinergics, and immunomodulators and blood vessels, while beta-2 receptors found...